What must be done to glutaraldehyde before use?

Glutaraldehyde is a high-level disinfectant commonly used for the sterilization of heat-sensitive medical devices and instruments, including flexible endoscopes. Before it can be effectively used as a disinfectant, it must undergo a process of activation. This activation typically involves mixing it with a solution that prepares it for use, usually by ensuring that the pH is suitable and the concentration is correct.

This activation is essential because glutaraldehyde in its raw form may not be as effective or may lead to varying results in disinfection. Ensuring that it is properly activated helps to guarantee the necessary antimicrobial properties are achieved for effective disinfection.

While heating, dilution, or filtration may remain important in particular contexts or with other substances, they do not apply specifically as mandatory steps before using glutaraldehyde for disinfection. The focus on activation underscores the importance of readying the chemical to perform at its optimum levels for safe and effective use in endoscope reprocessing.